Reactivity: | H,M,R |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | HPD rabbit polyclonal |
Gene Name: | 4-hydroxyphenylpyruvate dioxygenase |
Synonyms: | 4-HPPD, 4HPPD, GLOD3, HPD, HPPDase, PPD, 4-hydroxyphenylpyruvic acid oxidase, F protein |
Immunogen: | Recombinant protein corresponding to Mouse HPD |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1: 1800-1: 3600 | kidney |
Background
The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene.
Images
Immunohistochemistry analysis of paraffin-embedded human kidney using HPD (GB113484) at dilution of 1: 3600 | |
Immunohistochemistry analysis of paraffin-embedded mouse kidney using HPD (GB113484) at dilution of 1: 3600 | |
Immunohistochemistry analysis of paraffin-embedded rat kidney using HPD (GB113484) at dilution of 1: 3600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |