Your shopping cart is empty!
Anti-HRPT2/Parafibromin Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | HRPT2/Parafibromin rabbit polyclonal |
Gene Name: | Parafibromin |
Synonyms: | Cell division cycle protein 73 homolog, Hyperparathyroidism 2 protein homolog, Cdc73, C1orf28, FIHP, HYX, HRPT1, HRPT2, HPT JT |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Parafibromin |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 1000-1: 2000 | lung, liver |
IF | Mouse, Rat | 1: 300-1: 600 | testis, skeletal muscle, kidney |
Background
Parafibromin is a product of the hyperparathyroidism-jaw tumor syndrome gene HRPT2/CDC73, a putative tumor suppressor gene recently implicated in the autosomal dominant hyperparathyroidism-jaw tumor familial cancer syndrome, sporadic parathyroid cancer, and a minority of families with isolated hyperparathyroidism . Defects in CDC73 are causes of hyperparathyroidism type 1 (HRPT1) and hyperparathyroidism type 2 (HRPT2) as well as parathyroid carcinoma (PRTC) .
Images
| Immunohistochemistry analysis of paraffin-embedded mouse lung using Parafibromin (GB112529) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded mouse liver using Parafibromin (GB112529) at dilution of 1: 2000 |
| Immunofluorescent analysis of paraformaldehyde-fixed mouse testis using Parafibromin (GB112529) at dilution of 1: 600 |
| Immunofluorescent analysis of paraformaldehyde-fixed mouse skeletal muscle using Parafibromin (GB112529) at dilution of 1: 600 |
| Immunofluorescent analysis of paraformaldehyde-fixed mouse kidney using Parafibromin (GB112529) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
