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Anti-HSPA6 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | HSPA6 rabbit polyclonal antibody |
Gene Name: | Heat shock 70 kDa protein 6 |
Synonyms: | Heat shock 70 kDa protein B', HSPA6, Heat shock 70 kDa protein 6, HSP70B-Prime, OTTHUMP00000032372 |
Immunogen: | Recombinant protein corresponding to Mouse HSPA6 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Cytoskeleton, Secreted, Nucleus, Cell Membrane |
Predicted MW. | 71 kDa |
Observed MW. | 71 kDa |
Uniprot ID: | P17066 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | heart, brain, liver |
IHC/IF | Mouse, Rat | 1: 500-1: 2000 | lung |
Background
HSPA6 (also known as HSP70B) is a member of the HSPA (HSP70) family of heat-shock proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. Human HSP70B is known to be strictly inducible and shows very low or no basal expression levels in most cells. HSPA6 induction has been exploited as a reasonable biomarker of cellular stresses and its mRNA expression levels have been shown to be significantly induced against a variety of cellular stresses.
Images
| Western blot analysis of HSP70B (GB111660) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded mouse lung using HSP70B (GB111660) at dilution of 1: 1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat lung using HSP70B (GB111660) at dilution of 1: 1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
