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Anti-Hemoglobin subunit beta/ba1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Hemoglobin subunit beta/ba1 rabbit polyclonal antibody |
Gene Name: | Hemoglobin subunit beta |
Synonyms: | Beta-globin, CD113t-C, HBB, Hemoglobin beta chain, hemoglobin, beta, LVV-hemorphin-7, Spinorphin, Gamma 1 globin, HSGGL1, HBGR, HBGA, HBG1, HBA-T2, HBA |
Immunogen: | Recombinant protein corresponding to Human Hemoglobin subunit beta/ba1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Secreted |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 4000-1: 8000 | colon cancer, ovarian cancer |
Background
The hemoglobin molecule is a tetramer consisting of two alpha- and two beta-globin-like chains. HBB gene encodes hemoglobin beta chain. The hemoglobin chains, each with its own heme moiety, cooperate in binding and release of oxygen. Hemoglobin monomers have been found in blood and other tissues including macrophages, alveolar epithelial cells and brain. Defects in HBB have been linked to diseases including Sickle cell anemia, Beta-thalassemia, and Heinz body anemias. This antibody, raised against the full-length human HBB, recognizes the 13-16 kDa HBB in western blot analyses of human heart and placenta.
Images
 | Immunohistochemistry analysis of paraffin-embedded human colon cancer using HBB (GB113867) at dilution of 1: 8000 |
 | Immunohistochemistry analysis of paraffin-embedded human ovarian cancer using HBB (GB113867) at dilution of 1: 8000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
