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Anti-Hexokinase II Mouse mAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Hexokinase-2 |
Synonyms: | Hexokinase type II, HK II, Hk2, Muscle form hexokinase, muscle |
Immunogen: | Recombinant protein corresponding to Mouse Hexokinase II |
Uniprot ID: | O08528 |
Isotype: | IgG2b,κ |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 103 kDa / 103 kDa |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | heart, lung, skeletal muscle |
Background
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Images
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Western blot analysis of HKII (GB121063) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
