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Anti-IDH3G Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial |
Synonyms: | H IDHG, IDH3G |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse IDH3G |
Uniprot ID: | P70404 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 43 kDa / 50 kDa |
Product Usage Information
WB | Human, Mouse | 1: 500-1: 1000 | U-251 MG, NIH/3T3 |
Background
Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
Images
| Western blot analysis of IDH3G (GB114724) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
