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Anti-IFIT3/P60 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IFIT3/P60 rabbit polyclonal |
Gene Name: | Interferon-induced protein with tetratricopeptide repeats 3 |
Synonyms: | Glucocorticoid-attenuated response gene 49 protein, Garg49, CIG-49, Isg49, Ifi49, CIG49, IFI-60K, IFI60, IFIT 3, IFIT-4, IFIT3, IFIT4, IRG2, ISG-60, ISG60, RIG-G |
Immunogen: | Recombinant protein corresponding to Mouse IFIT3/P60 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 47 kDa |
Observed MW. | 60 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | kidney, liver, spleen |
Background
IFIT3 (IFN-induced protein with tetratricopeptide repeats 3), also known as IFIT-4, ISG-60 or RIG-G, is a 56 kDa IFN induced protein. IFIT3 has been identified to be associated with strong IFN antiviral activity. Upon RNA virus infection, IFIT3 is significantly induced, ectopic expression or knockdown of IFIT3 could, respectively, enhance or impair IFN regulatory factor 3 (IRF3)-mediated gene expression. IFIT3 thus may serve as an important modulator in innate immunity, revealing a new function of the IFIT family proteins.
Images
 | Western blot analysis of IFIT3 (GB113439) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
