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| Reactivity: | M,R & H |
| Applications: | WB & ICC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IGF1 rabbit polyclonal antibody |
Gene Name: | Insulin-like growth factor I |
Synonyms: | IGF1, IGF-I, IGF1A, IGFI, MGF, insulin like |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse IGF1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | P05017, P05019 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 1000-1: 2000 | brain, colon cancer, esophagus cancer, kidney, metrocarcinoma, spleen |
Background
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation.
Images
| Immunohistochemistry of paraffin embedded human esophagus cancer using IGF1 (GB11248) at dilution of 1:1000 (400x lens) |
| Immunohistochemistry of paraffin embedded human kidney using IGF1 (GB11248) at dilution of 1:1000 (400x lens) |
| Immunohistochemistry of paraffin embedded human metrocarcinoma using IGF1 (GB11248) at dilution of 1:1000 (400x lens) |
| Immunohistochemistry of paraffin embedded rat spleen using IGF1 (GB11248) at dilution of 1:1000 (400x lens) |
| Immunofluorescence of paraffin embedded human colon cancer using IGF1 (GB11248) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using IGF1 (GB11248) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using IGF1 (GB11248) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
