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Anti-IKB beta Rabbit pAb (100 μl)
| Reactivity: | M,R & R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IKB beta rabbit polyclonal |
Gene Name: | NF-kappa-B inhibitor beta |
Synonyms: | NFKBIB, IKBB, IkB-beta, IkappaBbeta, TRIP9, NFKB inhibitor beta |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse IKBβ |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1:300-1:600 | lung, kidney, colon, liver, testis |
IF | Human, Mouse, Rat | 1:300-1:600 | lung, kidney, colon, liver, testis |
Background
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
Images
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Immunohistochemistry analysis of paraffin-embedded human lung cancer using IKBβ (GB11306) at dilution of 1: 300 |
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Immunohistochemistry analysis of paraffin-embedded human colon using IKBβ (GB11306) at dilution of 1: 300 |
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Immunohistochemistry analysis of paraffin-embedded mouse lung using IKBβ (GB11306) at dilution of 1: 300 |
| Immunohistochemistry analysis of paraffin-embedded mouse kidney using IKBβ (GB11306) at dilution of 1: 300 |
| Immunohistochemistry analysis of paraffin-embedded rat liver using IKBβ (GB11306) at dilution of 1: 300 |
| Immunohistochemistry analysis of paraffin-embedded rat testis using IKBβ (GB11306) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
