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Anti-IKZF3 Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IKZF3 rabbit polyclonal |
Gene Name: | Zinc finger protein Aiolos |
Synonyms: | Ikaros family zinc finger protein 3, IKZF3, Zfpn1a3, Znfn1a3, Aiolos, Zinc finger protein subfamily 1A, member 3, Zinc finger protein subfamily 1A 3 |
Immunogen: | Recombinant protein corresponding to Mouse IKZF3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 1000-1: 4000 | spleen, thymus, lymph node |
IF | Mouse, Rat | 1: 1000-1: 3000 | spleen, thymus, lymph node, lung |
Background
IKZF3 is a hemopoietic zinc finger DNA-binding protein that acts as a central regulator of lymphoid differentiation and is implicated in leukemogenesis. IKZF3 may form homodimers or heterodimers and is known to interact with IKZF4 and IKZF5. A well known transcription factor, IKZF3, plays an important role in the regulation of B lymphocyte proliferation and differentiation and participates in chromatin remodeling. IKZF3 plays a role in the control of T cell death by regulating the expression of BCL2 in acute lymphoblastic leukemia.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse spleen using |
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Immunohistochemistry analysis of paraffin-embedded rat spleen using IKZF3 (GB111462) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded mouse thymus using IKZF3 (GB111462) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded rat thymus using IKZF3 (GB111462) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded rat lymph node using IKZF3 (GB111462) at dilution of 1: 2000 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse spleen using IKZF3 (GB111462) at dilution of 1: 2000 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat spleen using IKZF3 (GB111462) at dilution of 1: 2000 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse thymus using IKZF3 (GB111462) at dilution of 1: 2000 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat thymus using IKZF3 (GB111462) at dilution of 1: 2000 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse lymph node using IKZF3 (GB111462) at dilution of 1: 2000 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat lymph node using IKZF3 (GB111462) at dilution of 1: 2000 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat lung using IKZF3 (GB111462) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
