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Anti-IL-1 beta Mouse mAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Interleukin-1 beta |
Synonyms: | IL1B, IL-1, IL1-BETA, IL1F2, interleukin 1 beta |
Immunogen: | Recombinant protein corresponding to Rat IL-1 beta |
Uniprot ID: | Q63264 |
Isotype: | IgG1,k |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Secreted |
Predicted MW. / Observed MW. | 31 kDa / 28/35 kDa |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 300-1: 600 | tonsil, lung injury |
Background
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells.
Images
| Immunohistochemistry analysis of paraffin embedded rat lung injury using IL-1 beta (GB12115) at dilution of 1: 50 |
| Immunohistochemistry analysis of paraffin embedded mouse lung injury using IL-1 beta (GB12115) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded human tonsil using IL-1 beta (GB12115) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
