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Anti-IL-27-A Rabbit pAb (100 μl)
| Reactivity: | M,R & H,M |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IL-27-A rabbit polyclonal antibody |
Gene Name: | Interleukin-27 subunit alpha |
Synonyms: | Il27, IL27A, Interleukin 27, Interleukin 27 subunit alpha, Interleukin 30, IL30, IL 27 p28 subunit, IL27p28 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse IL27A |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: |
Product Usage Information
WB | Mouse, Rat | 1:500-1:1000 | liver, spleen, lung |
IHC/IF | Human, Mouse | 1: 400-1: 1600 | epityphlon, Immune spleen, lymph node |
Background
Interleukin 27 (IL-27) is a member of the IL-12 cytokine family. It is a heterodimeric cytokine that is composed of two distinct genes, Epstein-Barr virus-induced gene 3 (EBI3) and IL-27p28. IL-27 is expressed by antigen presenting cells and interacts with a specific cell-surface receptor complex known as IL-27 receptor (IL-27R). This receptor consists of two proteins, IL-27ɑ and gp130. IL-27 induces differentiation of the diverse populations of T cells in the immune system and also upregulates IL-10.
Images
| Western blot analysis of IL-27-A (GB11662) at dilution of 1: 1000 |
 | Immunohistochemistry of paraffin embedded human epityphlon using IL-27A (GB11662) at dilution of 1: 400 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse Immune spleen using IL-27A (GB11662) at dilution of 1: 800 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse spleen using IL-27A (GB11662) at dilution of 1: 400 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse lymph node using IL-27A (GB11662) at dilution of 1: 800 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse spleen using IL-27A (GB11662) at dilution of 1: 800 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
