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Anti-IL-5RA Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IL-5RA rabbit polyclonal |
Gene Name: | Interleukin-5 receptor subunit alpha |
Synonyms: | CD125, CDw125, HSIL5R3, IL 5 receptor subunit alpha, IL 5R alpha, IL 5R subunit alpha, IL5R, IL5RA, IL-5RA, interleukin 5 receptor, alpha |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse IL-5RA |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 47 kDa |
Observed MW. | 55 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse | 1: 300-1: 600 | pancreas |
Background
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5(IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.
Images
 | Western blot analysis of IL-5RA (GB113699) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
