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| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | |
| Clonality: | |
| Gene Name: | Interleukin-6 |
Synonyms: | IL6, BSF2, HGF, HSF, IFNB2, IL-6, BSF-2, CDF, IFN-beta-2, interleukin 6 |
Immunogen: | Recombinant protein corresponding to Mouse IL-6 |
Uniprot ID: | P08505 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 24 kDa / 21-24 kDa |
Product Usage Information
WB | Human, Mouse | 1: 100-1: 300 | RAW264.7, THP-1 |
Background
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.
Images
| WB analysis of IL-6(GB12117). |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
