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Anti-ILF3/NF90 Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ILF3/NF90 rabbit polyclonal antibody |
Gene Name: | Interleukin enhancer-binding factor 3 |
Synonyms: | CBTF, DRBF, DRBP76, ILF3, M phase phosphoprotein 4, MMP4, MPHOSPH4, MPP4, NF AT 90, NF110, NF90, NFAR, NFAR 1, NFAR2, TCP110, TCP80 |
Immunogen: | Recombinant protein corresponding to Mouse ILF3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 96 kDa |
Observed MW. | 110 kDa |
Uniprot ID: | Q12906, Q9Z1X4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 500-1: 1000 | lymph node |
Background
This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein was first discovered to be a subunit of the nuclear factor of activated T-cells (NFAT); a transcription factor required for T-cell expression of interleukin 2. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. These proteins have been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth; possibly by inhibition of mRNA stabilization.
Images
| Western blot analysis of ILF3 (GB111976) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
