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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IRF7 rabbit polyclonal antibody |
Gene Name: | Interferon regulatory factor 7 |
Synonyms: | Irf7 |
Immunogen: | Recombinant protein corresponding to Mouse IRF7 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Uniprot ID: | F7FGY2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 1000-1: 3000 | liver, lung, spleen, thymus |
Background
IRF7 is the key transcriptional regulator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes and IFN-stimulated genes by binding to an interferon-stimulated response element in their promoters. Can efficiently activate both the IFN-beta and the IFN-alpha genes and mediate their induction via both the virus-activated, MyD88-independent pathway and the TLR-activated, MyD88-dependent pathway.
Images
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Immunohistochemistry of paraffin embedded rat liver using IRF7 (GB111169) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat spleen using IRF7 (GB111169) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat thymus using IRF7 (GB111169) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded mouse lung using IRF7 (GB111169) at dilution of 1:2000 (400x lens) |
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Immunofluorescence of paraffin embedded mouse spleen using IRF7 (GB111169) at dilution of 1:2000 (400x lens) |
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Immunofluorescence of paraffin embedded rat liver using IRF7 (GB111169) at dilution of 1:2000 (400x lens) |
 | Immunofluorescence of paraffin embedded rat spleen using IRF7 (GB111169) at dilution of 1:2000 (400x lens) |
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Immunofluorescence of paraffin embedded rat thymus using IRF7 (GB111169) at dilution of 1:2000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
