Anti-IRF8 Rabbit pAb (100 μl)

Anti-IRF8 Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB113417-100
Availability: In Stock
$259.00
-+
Reactivity: H,M,R    
Applications: WB    
Host Species: Rabbit    
Clonality: Polyclonal    
Full Name:

IRF8 rabbit polyclonal

Gene Name:

Interferon regulatory factor 8

Synonyms:

H ICSBP, ICSBP, ICSBP1, IRF-8, IRF8, MYLS

Immunogen:

Recombinant protein corresponding to

Mouse IRF8

Isotype:

IgG

Purity:

Affinity purification

Predicted MW.

48 kDa

Observed MW.

50 kDa

Uniprot ID:

Q02556, P23611, Q5NUI4




Product Usage Information

Applications

Species

Dilution

Positive tissue

WB

Human, Mouse, Rat

1: 1000-1: 2000

lymph node, spleen, thymus




Background

IRF8 also named as ICSBP1, is a transcription factor of the IFN regulatory factor (IRF) family. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. IRF8 specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the IFN consensus sequence (ICS)). It plays a negative regulatory role in cells of the immune system. It is predominantly in lymphoid tissues. 




Images

Western blot analysis of IRF8 (GB113417) 

at dilution of 1: 2000




Storage

StorageStore at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


Related Products


LifeSct © 2025

Publications

text_heading

Our Location

405 East Gude Dr., Suite 205, Rockville, MD 20850, USA

1-301-890-6420