Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | IgM Chain C rabbit polyclonal antibody |
Gene Name: | Immunoglobulin heavy constant mu |
Synonyms: | Ighm, Igh-6, AGM1, Constant region of heavy chain of IgM, VH, MU |
Immunogen: | Recombinant protein corresponding to Mouse IgM Chain C |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Secreted |
Predicted MW. | 50 kDa |
Observed MW. | 72 kDa |
Uniprot ID: | P01872 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | bone marrow |
IHC/IF | Human, Mouse, Rat | 1: 350-1: 1500 | Hodgkin's lymphoma, lymph node, splenitis |
Background
IgM antibodies play an important role in primary defense mechanisms. They have been shown to be involved in early recognition of external invaders like bacteria and viruses, cellular waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions.
Images
Western blot analysis of IgM chain C (GB112040) at dilution of 1: 500 | |
Immunohistochemistry of paraffin embedded mouse splenitis using IgM Chain C (GB112040) at dilution of 1: 350 (250x lens) | |
Immunofluorescence of paraffin embedded human Hodgkin's lymphoma using IgM Chain C (GB112040) at dilution of 1: 400 (300x lens) | |
Immunofluorescence of paraffin embedded rat lymph node using IgM Chain C (GB112040) at dilution of 1: 400 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |