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Anti-Integrin beta 1 Rabbit pAb (100 μl)
| Reactivity: | R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Integrin beta 1 rabbit polyclonal antibody |
Gene Name: | Integrin beta-1 |
Synonyms: | Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29, ITGB1, FNRB, MDF2, MSK12 |
Immunogen: | Recombinant protein corresponding to Mouse Integrin beta 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 88 kDa |
Observed MW. | 130 kDa |
Uniprot ID: | P09055, P49134 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1:500-1:1000 | lung, kidney |
Background
Integrin beta-1 (ITGB1), also known as CD29, is a cell surface receptor. This integrin associates with integrins alpha 1 and 2 to form integrin complexes which function as collagen receptors. It also forms dimers with integrin alpha 3 to form integrin receptors for netrin 1 and reelin. Integrin beta 1 is expressed as at least four different isoforms. In cardiac muscle and skeletal muscle, the integrin beta-1D isoform is specifically expressed, and localizes to costameres, where it aids in the lateral force transmission from the Z-discs to the extracellular matrix. Abnormal levels of integrin beta-1D have been found in limb girdle muscular dystrophy and polyneuropathy.
Images
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Western blot analysis of CD29 (GB11537) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
