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Anti-Inversin Rabbit pAb (100 μl)
| Reactivity: | H & H |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Inversin rabbit polyclonal antibody |
Gene Name: | Inversin |
Synonyms: | Inversion of embryo turning homolog, Nephrocystin-2, INVS, INV, NPHP2, Inversin |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Inversin |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. | 118 kDa |
Observed MW. | 118 kDa |
Uniprot ID: | Q9Y283 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1:500-1:1000 | HEK293, HepG2, A549, K562 |
IHC/IF | Human | 1:1000-1:3000 | colon, liver, liver cancer, lung, renal cancer |
Background
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2.
Images
| Western blot analysis of Inverin (GB111298) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded human colon using INVS (GB111298) at dilution of 1: 1500 (400x lens) |
| Immunohistochemistry of paraffin embedded human liver using INVS (GB111298) at dilution of 1: 1500 (400x lens) |
| Immunohistochemistry of paraffin embedded human renal cancer using INVS (GB111298) at dilution of 1: 1500 (400x lens) |
| Immunofluorescence of paraffin embedded human liver cancer using INVS (GB111298) at dilution of 1: 1500 (400x lens) |
| Immunofluorescence of paraffin embedded human lung using INVS (GB111298) at dilution of 1: 1500 (400x lens) |
| Immunofluorescence of paraffin embedded human renal cancer using INVS (GB111298) at dilution of 1: 1500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
