Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Ionotropic Glutamate receptor 2 antibody |
Gene Name: | Glutamate receptor 2 |
Synonyms: | Gria2, GRIA2, GLUR2, GLURB, GluA2, GluR-K2, HBGR2, Glutamate ionotropic receptor AMPA type subunit 2 |
Immunogen: | Recombinant protein corresponding to Mouse GRIA2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membran, Cytoplasm |
Uniprot ID: | P23819, P19491 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 3000 | brain, epencephalon |
Background
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.
Images
Immunohistochemistry of paraffin embedded mouse brain using GLUA2 (GB11770) at dilution of 1:3000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using GLUA2 (GB11770) at dilution of 1:3000 (400x lens) | |
Immunofluorescence of paraffin embedded mouse brain using GLUA2 (GB11770) at dilution of 1:500 (400x lens) | |
Immunofluorescence of paraffin embedded mouse epencephalon using GLUA2 (GB11770) at dilution of 1:500 (400x lens) | |
Immunofluorescence of paraffin embedded rat brain using GLUA2 (GB11770) at dilution of 1:500 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |