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| Reactivity: | M |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Junctophilin-1 |
Synonyms: | JP-1, JP1, JPH1, junctophilin 1, Junctophilin type 1 |
Immunogen: | Recombinant protein corresponding to Mouse JP-1 |
Uniprot ID: | Q9ET80 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Product Usage Information
IHC/IF | Mouse | 1: 2000-1: 4000 | tongue, skeletal muscle |
Background
Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes.
Images
| Immunohistochemistry of paraffin embedded mouse tongue using JP-1 (GB114229) at dilution of 1: 2000 |
| Immunohistochemistry of paraffin embedded mouse skeletal muscle using JP-1 (GB114229) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
