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Anti-KAT5 / Tip60 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | KAT5 / Tip60 rabbit polyclonal antibody |
Gene Name: | Histone acetyltransferase KAT5 |
Synonyms: | 60 kDa Tat-interactive protein, Tip60, Histone acetyltransferase HTATIP, KAT5, Lysine acetyltransferase 5, PLIP, TIP, cPLA2, ESA1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse KAT5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. | 59 kDa |
Observed MW. | 55 kDa |
Uniprot ID: | Q92993, Q8CHK4, Q99MK2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1:500-1:1000 | heart, liver |
IHC/IF | Mouse, Rat | 1:300-1:800 | brain, heart, lung, testis |
Background
KAT5, also named as The histone acetyltransferase (HAT) Tat interactive protein 60 kD belongs to the MYST protein family that contains atypical zinc finger and histone acetyltransferase domains. Also, KAT5 contains a chromodomain. KAT5 is a catalytic subunit of the NuA4 histone acetyltransferase complex. The NuA4 HAT complex plays a role in transcriptional activation of select genes mainly by acetylation of nucleosomal histone H4 and H2A, which influence nucleosome-DNA interaction and promotes interaction of the modified histones with other proteins that could regulate transcription positively.
Images
| Western blot analysis of KAT5 (GB111964) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded mouse brain using KA75 (GB111964) at dilution of 1: 400 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse lung using KA75 (GB111964) at dilution of 1: 400 (400x lens) |
| Immunohistochemistry of paraffin embedded rat brain using KA75 (GB111964) at dilution of 1: 400 (400x lens) |
| Immunohistochemistry of paraffin embedded rat heart using KA75 (GB111964) at dilution of 1: 400 (400x lens) |
| Immunohistochemistry of paraffin embedded rat lung using KA75 (GB111964) at dilution of 1: 400 (400x lens) |
| Immunohistochemistry of paraffin embedded rat testis using KA75 (GB111964) at dilution of 1: 400 (300x lens) |
| Immunofluorescence of paraffin embedded mouse testis using KA75 (GB111964) at dilution of 1: 400 (340x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
