Reactivity: | H,M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Intermediate conductance calcium-activated potassium channel protein 4 |
Synonyms: | hIKCa1, hKCa4, hSK4, IK1, IKCA1, KCa3.1, KCA4, KCNN4, Putative Gardos channel, SK4, SKCa 4, SKCa4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse KCNN4 |
Uniprot ID: | O89109 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 48 kDa / 48 kDa |
Product Usage Information
WB | Human, Mouse | 1: 800-1: 1200 | thymus |
Background
Forms a voltage-independent potassium channel that is activated by intracellular calcium . Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells . Plays a role in the late stages of EGF-induced macropinocytosis (By similarity).
Images
Western blot analysis of KCNN4 (GB114347) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |