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Anti-KDM1/LSD1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | KDM1/LSD1 rabbit polyclonal antibody |
Gene Name: | Lysine-specific histone demethylase 1A |
Synonyms: | BRAF35-HDAC complex protein BHC110, Flavin-containing amine oxidase domain-containing protein 2, Kdm1a, Aof2, Kiaa0601, Lsd1 |
Immunogen: | Recombinant protein corresponding to Mouse KDM1/LSD1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. | 93 kDa |
Observed MW. | 110 kDa |
Uniprot ID: | O60341, Q6ZQ88 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | testis, placenta |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 3000 | brain, breast cancer, colon, kidney, liver, lung cancer, placenta, testis |
Background
Gene activation and repression is specifically regulated by histone methylation status at distinct lysine residues. Lysine specific demethylase 1 (KDM1/LSD1) is a long-sought histone demethylase that specifically demethylates mono and di methyl histone H3 at K4 and K9. Thus KDM1 is a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor.
Images
| Western blot analysis of LSD1 (GB112427) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded human lung cancer using LSD1 (GB112427) at dilution of 1: 500 (400x lens) |
| Immunohistochemistry of paraffin embedded human placenta using LSD1 (GB112427) at dilution of 1: 500 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse brain using LSD1 (GB112427) at dilution of 1: 500 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse colon using LSD1 (GB112427) at dilution of 1: 500 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse kidney using LSD1 (GB112427) at dilution of 1: 500 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse placenta using LSD1 (GB112427) at dilution of 1: 500 (400x lens) |
| Immunofluorescence of paraffin embedded human breast cancer using LSD1 (GB112427) at dilution of 1: 650 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse brain using LSD1 (GB112427) at dilution of 1: 650 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse placenta using LSD1 (GB112427) at dilution of 1: 650 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse testis using LSD1 (GB112427) at dilution of 1: 650 (400x lens) |
 | Immunofluorescence of paraffin embedded rat liver using LSD1 (GB112427) at dilution of 1: 650 (400x lens) |
| Immunofluorescence of paraffin embedded rat placenta using LSD1 (GB112427) at dilution of 1: 650 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
