Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | CLOCK-interacting pacemaker |
Synonyms: | KIAA1737, CIPC |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse KIAA1737/CIPC |
Uniprot ID: | Q8R0W1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 46 kDa / 50 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 2000-1: 3000 | heart |
Background
Transcriptional repressor which may act as a negative-feedback regulator of CLOCK-ARNTL/BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate ARNTL/BMAL1-dependent phosphorylation of CLOCK. However, the physiogical relevance of these observations is unsure, since experiments in knockout mice showed that CIPC is not critially required for basic circadian clock.
Images
Western blot analysis of KIAA1737 (GB115401) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |