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Anti-KMT1A / SUV39H1 Rabbit pAb (100 μl)
| Reactivity: | H,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | SUV39H1 rabbit polyclonal antibody |
Gene Name: | Histone-lysine N-methyltransferase SUV39H1 |
Synonyms: | Suv39h1, SUV39H1, H3-K9-HMTase 1, KMT1A, MG44, SUV39H, suppressor of variegation 3-9 homolog 1 |
Immunogen: | Recombinant protein corresponding to Mouse SUV39H1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | O54864 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Rat | 1: 500-1: 2000 | brain, breast cancer, epencephalon, kidney, lung |
Background
Histone-lysine N-methyltransferase SUV39H1 is an enzyme encoded by the SUV39H1 gene. This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression.
Images
 | Immunohistochemistry of paraffin embedded rat epencephalon using SUV39H1 (GB11793) at dilution of 1:500 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat kidney using SUV39H1 (GB11793) at dilution of 1:500 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat lung using SUV39H1 (GB11793) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded human breast cancer using SUV39H1 (GB11793) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using SUV39H1 (GB11793) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded rat lung using SUV39H1 (GB11793) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
