Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | KPNA1 rabbit polyclonal |
Gene Name: | Importin subunit alpha-5 |
Synonyms: | Importin alpha-S1, Karyopherin subunit alpha-1, Nucleoprotein interactor 1, NPI-1, RAG cohort protein 2, SRP1-beta, Kpna1, Rch2, Impα5, IPOA5, SRP1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse KPNA1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
IHC/IF | Mouse | 1: 3000-1: 6000 | testis, placenta |
Background
Importins (alpha and beta) are transport factors that transport proteins into the nucleus. alpha importins function by binding transcription factors at nuclear localization sequences (NLS), and associating with importin beta subunits to translocate through the nuclear pore. Six isoforms of alpha importins have been described in human. Importin alpha 5 is the predominant importin in adult CNS and is essential for differentiation and viability of neural cells.
Images
Immunohistochemistry analysis of paraffin-embedded mouse testis using KPNA1 (GB113061) at dilution of 1: 6000 | |
Immunohistochemistry analysis of paraffin-embedded mouse placenta using KPNA1 (GB113061) at dilution of 1: 6000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |