Reactivity: | M,R & M |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Kallikrein 7/KLK7 rabbit polyclonal |
Gene Name: | Kallikrein-7 |
Synonyms: | Serine protease 6, Stratum corneum chymotryptic enzyme, Thymopsin, Klk7, Prss6, Scce |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Kallikrein 7/KLK7 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 27 kDa |
Observed MW. | 27 kDa |
Uniprot ID: |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | skin |
IHC/IF | Mouse | 1: 800-1: 1600 | skin |
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein.
Images
Western blot analysis of KLK7 (GB112987) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin-embedded mouse skin using KLK7 (GB112987) at dilution of 1: 1600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |