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Anti-LIM Kinase 1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | LIM Kinase 1 rabbit polyclonal antibody |
Gene Name: | LIM domain kinase 1 |
Synonyms: | LIMK-1, KIZ-1, Limk1, Limk, LIM motif containing protein kinase |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse LIM Kinase 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 73 kDa |
Observed MW. | 73 kDa |
Uniprot ID: | P53667, P53668, P53669 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | colon, lung |
Background
LIMK1 is a protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. LIMK1 may be involved in brain development; it is highly expressed in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.
Images
| Western blot analysis of LIMKinase (GB112215) at dilution of 1: 500 |
| Western blot analysis of LIMKinase (GB112215) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
