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| Reactivity: | H & H |
| Applications: | WB & ICC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Lysyl oxidase homolog 2 |
Synonyms: | LOXL2, LOR2, WS9-14, lysyl oxidase like 2, LOR |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse LOXL2 |
Uniprot ID: | P58022 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 87 kDa / 87 kDa |
Product Usage Information
WB | Human | 1: 500-1: 1000 | HeLa, Lncap, 293T |
ICC/IF | Human | 1: 50-1: 200 | Hela |
Background
Lysyl oxidase homolog 2 is an enzyme encoded by the LOXL2 gene. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function.
Images
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Western blot analysis of LOXL2 (GB11849) at dilution of 1: 500 |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed HeLa cells using LOXL2(GB11849) at dilution of 1: 50-1: 200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
