Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | LYRIC rabbit polyclonal antibody |
Gene Name: | Protein LYRIC |
Synonyms: | 3D3/LYRIC, Lysine-rich CEACAM1 co-isolated protein, Metadherin, Metastasis adhesion protein, Mtdh, Lyric |
Immunogen: | Recombinant protein corresponding to Mouse LYRIC |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Endoplasmic reticulum, Membrane, Nucleus, Cell junction |
Uniprot ID: | Q86UE4, Q80WJ7, Q9Z1W6 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 1500-1: 4000 | brain, colon, heart, kidney, liver cancer, lung cancer, testis |
Background
LYRIC, also known as AEG-1, is a single-pass transmembrane protein with its gene located at chromosome 8q22 , the abnormalities of which have been identified in several tumor types. MTDH is over expressed in a number of malignancies, such as breast cancer, malignant glioma, and neuroblastoma , and its over expression is associated with poor clinical outcome. MTDH plays an important role in the regulation of carcinogenesis and tumor progression.
Images
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Immunohistochemistry of paraffin embedded human colon using LYRIC (GB111269) at dilution of 1:2000 (400x lens) |
Immunohistochemistry of paraffin embedded human lung cancer using LYRIC (GB111269) at dilution of 1:2000 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse heart using LYRIC (GB111269) at dilution of 1:2000 (400x lens) | |
Immunohistochemistry of paraffin embedded rat kidney using LYRIC (GB111269) at dilution of 1:2000 (400x lens) | |
Immunohistochemistry of paraffin embedded rat testis using LYRIC (GB111269) at dilution of 1:2000 (400x lens) | |
Immunofluorescence of paraffin embedded human liver cancer using LYRIC (GB111269) at dilution of 1:2000 (400x lens) | |
Immunofluorescence of paraffin embedded mouse brain using LYRIC (GB111269) at dilution of 1:2000 (400x lens) | |
Immunofluorescence of paraffin embedded mouse heart using LYRIC (GB111269) at dilution of 1:2000 (400x lens) | |
Immunofluorescence of paraffin embedded rat testis using LYRIC (GB111269) at dilution of 1:2000 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |