Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Lingo1 rabbit polyclonal antibody |
Gene Name: | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 |
Synonyms: | Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A, Lingo1, Lern1, Lrrn6a |
Immunogen: | Recombinant protein corresponding to Mouse Lingo1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 69 kDa |
Observed MW. | 83 kDa |
Uniprot ID: | Q9D1T0 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | brain, cerebral cortex, hippocampus |
Background
LINGO1 is a functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. It is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.
Images
Western blot analysis of Lingo1 (GB111456) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |