Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Lyn rabbit polyclonal antibody |
Gene Name: | Tyrosine-protein kinase Lyn |
Synonyms: | LYN, LYN proto-oncogene, Src family tyrosine kinase, JTK8, p53Lyn, p56Lyn |
Immunogen: | Recombinant protein corresponding to Mouse Tyrosine-protein kinase Lyn |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 59 kDa |
Observed MW. | 56 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, spleen, lung |
Background
Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues, liver, and adipose tissue. In various hematopoietic cells, Lyn has emerged as a key enzyme involved in the regulation of cell activation. In these cells, a small amount of LYN is associated with cell surface receptor proteins, including the B cell antigen receptor (BCR), CD40 or CD19. The abbreviation Lyn is derived from Lck/Yes novel tyrosine kinase, Lck and Yes also being members of the Src kinase family.
Images
Western blot analysis of LYN (GB11646) at dilution of 1: 500 |