Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | M-CSF rabbit polyclonal antibody |
Gene Name: | Macrophage colony-stimulating factor 1 |
Synonyms: | CSF-1, M-CSF, MCSF, Lanimostim, Processed macrophage colony-stimulating factor 1, CSF1 |
Immunogen: | Recombinant protein corresponding to Human M-CSF |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Secreted |
Uniprot ID: | P09603, P07141 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 400-1: 2000 | bone, brain, colon, colon cancer, lymph node, spleen, tonsil |
Background
The Macrophage Colony Stimulating Factor (M-CSF, also called CSF-1) is a disulfide-linked homodimer produced by a variety of cells including fibroblasts, macrophages, bone marrow stromal cells and endothelial cells. M-CSF regulates macrophage survival, proliferation and differentiation. M-CSF also enhances macrophage killing of tumor cells and microorganisms and regulates cytokine production from macrophages.
Images
Immunohistochemistry of paraffin embedded human colon using CSF1 (GB111205) at dilution of 1:900 (400x lens) |
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Immunohistochemistry of paraffin embedded human colon cancer using CSF1 (GB111205) at dilution of 1:900 (400x lens) | |
Immunohistochemistry of paraffin embedded human tonsil using CSF1 (GB111205) at dilution of 1:900 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse bone using CSF1 (GB111205) at dilution of 1:450 (400x lens) | |
Immunofluorescence of paraffin embedded human lymph node using CSF1 (GB111205) at dilution of 1:900 (400x lens) | |
Immunofluorescence of paraffin embedded mouse bone using CSF1 (GB111205) at dilution of 1:900 (400x lens) | |
Immunofluorescence of paraffin embedded mouse brain using CSF1 (GB111205) at dilution of 1:900 (400x lens) | |
Immunofluorescence of paraffin embedded rat spleen using CSF1 (GB111205) at dilution of 1:900 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |