Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Cation-independent mannose-6-phosphate receptor |
Synonyms: | CI Man-6-P receptor, CI-MPR, M6PR, 300 kDa mannose 6-phosphate receptor, MPR 300, nsulin-like growth factor 2 receptor, IGF-II receptor, CD222, Igf2r, M6P/IGF2R |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse M6PR (cation independent) |
Uniprot ID: | Q07113 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 274 kDa / 300 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, kidney, heart |
Background
IGF2R, also named as MPRI, CI Man-6-P receptor, CI-MPR, M6PR, IGF-II receptor, M6P/IGF2R, MPR 300 and CD222, belongs to the MRL1/IGF2R family. IGF2R transports of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. IGF2R is a lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.
Images
Western blot analysis of M6PR (cation independent) (GB111801) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |