Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Cation-dependent mannose-6-phosphate receptor |
Synonyms: | CD Man-6-P receptor, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPR 46, M6pr, 46mpr |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse M6PR |
Uniprot ID: | P24668 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 31 kDa / 46 kDa |
Product Usage Information
WB | Human | 1: 300-1: 500 | HeLa, HepG2, A549 |
Background
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.
Images
Western blot analysis of M6PR (GB114577) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |