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| Reactivity: | H,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MAEA rabbit polyclonal antibody |
Gene Name: | E3 ubiquitin-protein transferase MAEA |
Synonyms: | Erythroblast macrophage protein, Macrophage erythroblast attacher, aea, Emp, GID9, HLC-10, PIG5, Proliferation inducing gene 5 |
Immunogen: | Recombinant protein corresponding to Mouse MAEA |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm, Nucleus |
Uniprot ID: | Q7L5Y9, Q5RKJ1 |
Product Usage Information
IHC/IF | Human, Rat | 1: 600-1: 1200 | brain |
Background
This gene product mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. This protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Two immunologically related isoforms of erythroblast macrophage protein with apparent molecular weights of 33 kD and 36 kD were detected in macrophage membranes, this gene encodes the larger isoform.
Images
| Immunofluorescence analysis of paraffin embedded rat brain using MAEA (GB111748) at dilution of 1:600 |
| Immunofluorescent analysis of paraformaldehyde-fixed human skin using MAEA (GB111748) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraformaldehyde-fixed human breast using MAEA (GB111748) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraformaldehyde-fixed rat colon using MAEA (GB111748) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraformaldehyde-fixed rat brain using MAEA (GB111748) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
