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Anti-MAGEA4 Rabbit pAb (100 μl)
| Reactivity: | H,M & H |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MAGEA4 rabbit polyclonal |
Gene Name: | Melanoma-associated antigen 4 |
Synonyms: | Cancer/testis antigen 1.4, CT1.4, MAGE 4 antigen, MAGE 41, MAGE 41 antigen, MAGE X2, MAGE X2 antigen, MAGE4, MAGE4A, MAGE4B, MAGEA4, melanoma antigen family A, 4, Melanoma associated antigen 4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human MAGEA4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Predicted MW. | 35 kDa |
Observed MW. | 45 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
| WB | Human, Mouse | 1: 500-1: 800 | testis |
IHC | Human | 1: 200-1: 700 | placenta, lung cancer, colon |
Background
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.
Images
| Western blot analysis of MAGEA4 (GB113341) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin-embedded human lung cancer using MAGEA4 (GB113341) at dilution of 1: 700 |
| Immunohistochemistry analysis of paraffin-embedded human colon using MAGEA4 (GB113341) at dilution of 1: 700 |
| Immunohistochemistry analysis of paraffin-embedded human placenta using MAGEA4 (GB113341) at dilution of 1: 700 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
