Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | MALT1 rabbit polyclonal antibody |
Gene Name: | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog |
Synonyms: | Malt1, MALT1, IMD12, MLT, MLT1, PCASP1, MALT1 paracaspase |
Immunogen: | Recombinant protein corresponding to Mouse MALT1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | Q2TBA3 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 250-1: 2000 | lymph node, spleen, thymus |
Background
Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.
Images
Immunohistochemistry of paraffin embedded mouse lymph node using MALT1 (GB11790) at dilution of 1:1000 (400x lens) | |
Immunohistochemistry of paraffin embedded rat lymph node using MALT1 (GB11790) at dilution of 1:1000 (400x lens) | |
Immunofluorescence of paraffin embedded mouse spleen using MALT1 (GB11790) at dilution of 1:500 (400x lens) | |
Immunofluorescence of paraffin embedded mouse thymus using MALT1 (GB11790) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded rat lymph node using MALT1 (GB11790) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded rat spleen using MALT1 (GB11790) at dilution of 1:500 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |