Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | MAP4K5 rabbit polyclonal antibody |
Gene Name: | Mitogen-activated protein kinase kinase kinase kinase 5 |
Synonyms: | GCKR, KHS, KHS1, MAP4K5, MAPKKKK5, MEK kinase kinase 5, MEKKK 5 |
Immunogen: | Recombinant protein corresponding to Mouse MAP4K5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 95 kDa |
Observed MW. | 95 kDa |
Uniprot ID: | Q8BPM2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 300-1: 600 | testis, cerebellum, ovary |
Background
MAP4K5, a member of the STE20 subfamily of Ser/Thr protein kinases, may play a role in the response to environmental stress. It appears to act upstream of the JUN N-terminal pathway. MAP4K5 interacts with both SH3 domains of the adapter proteins CRK and CRKL. This cytoplasmic protein is ubiquitously expressed in all tissues examined, with high levels in the ovary, testis and prostate.
Images
Western blot analysis of MAP4K5 (GB114028) at dilution of 1: 300 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |