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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MAR6 rabbit polyclonal antibody |
Gene Name: | Retrotransposon Gag-like protein 6 |
Synonyms: | Mammalian retrotransposon-derived protein 6, Protein LDOC1L, Protein Sushi-15E3, Rtl6, Ldoc1l, MAR6 |
Immunogen: | Recombinant protein corresponding to Mouse MAR6 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | Q505G4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 700-1: 1400 | brain, neonatal mouse's brain, neonatal rat's brain |
Background
LDOC1 is a 146 amino acid nuclear protein that contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is downregulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kB (NF-kB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. LDOC1L (Leucine zipper protein down-regulated in cancer cells-like), also known as MART6 (Mammalian retrotransposon-derived protein 6), is a 239 amino acid protein that belongs to the LDOC1 family.
Images
| Immunohistochemistry of paraffin embedded mouse neonatal mouse's brain using LDOCL (GB112173) at dilution of 1:1400 (400x lens) |
| Immunohistochemistry of paraffin embedded rat brain using LDOCL (GB112173) at dilution of 1:1400 (400x lens) |
| Immunohistochemistry of paraffin embedded rat neonatal rat's brain using LDOCL (GB112173) at dilution of 1:1400 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
