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Anti-MARK1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MARK1 rabbit polyclonal antibody |
Gene Name: | Serine/threonine-protein kinase MARK1 |
Synonyms: | ELKL motif serine/threonine-protein kinase 3, MAP/microtubule affinity-regulating kinase 1, PAR1 homolog c, Par-1c, mPar-1c, Mark1, Emk3 |
Immunogen: | Recombinant protein corresponding to Mouse MARK1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 88 kDa |
Observed MW. | 95 kDa |
Uniprot ID: | Q8VHJ5, O08678 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | brain, cerebral cortex |
Background
MARK1 is thought to play a role in the stability of the microtubule matrix of the cytoskeleton. MARK1 is activated by phosphorylation of Thr215 by LKB1 in complex with STRAD and MO25. Localized to the cytoskeleton, MARK1 contains one kinase-associated (KA1) domain, one protein kinase domain and one UBA domain. Expressed as three isoforms produced by alternative splicing, MARK1 is found with highest levels in brain, skeletal muscle and heart.
Images
| Western blot analysis of MARK1 (GB112224) at dilution of 1: 500 |
| Western blot analysis of MARK1 (GB112224) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
