Anti-MCM2 Rabbit pAb (100 μl)

Anti-MCM2 Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB111162-100
Availability: In Stock
$259.00
-+
Reactivity: H,M,R & H,M,R    
Applications: WB & IHC/IF    
Host Species: Rabbit    
Clonality: Polyclonal    
Full Name:

MCM2 rabbit polyclonal antibody

Gene Name:

DNA replication licensing factor MCM2

Synonyms:

Minichromosome maintenance protein 2 homolog, Nuclear protein BM28, Mcm2, Bm28, Cdcl1, Kiaa0030, Mcmd2

Immunogen:

KLH conjugated Synthetic peptide corresponding to Mouse MCM2

Isotype:

IgG

Purity:

Affinity purification

Subcellular location:

Nucleus

Predicted MW.

102 kDa

Observed MW.

130 kDa

Uniprot ID:

P49736, P97310, D3ZP96




Product Usage Information

Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

thymus

IHC/IF

Human, Mouse, Rat

1: 1000-1: 4000

brain, colon cancer, lung, lung cancer, thymus




Background

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. 




Images

Western blot analysis of MCM2 (GB111162) at dilution of 1: 500

Immunohistochemistry of paraffin embedded human colon cancer using MCM2 (GB111162) at dilution of 1: 4000 (400x lens)

Immunohistochemistry of paraffin embedded human lung cancer using MCM2 (GB111162) at dilution of 1: 4000 (400x lens)

Immunohistochemistry of paraffin embedded mouse brain using MCM2 (GB111162) at dilution of 1: 2000 (400x lens)

Immunohistochemistry of paraffin embedded mouse thymus using MCM2 (GB111162) at dilution of 1: 4000 (400x lens)

Immunohistochemistry of paraffin embedded rat lung using MCM2 (GB111162) at dilution of 1: 2000 (400x lens)

Immunohistochemistry of paraffin embedded rat thymus using MCM2 (GB111162) at dilution of 1: 4000 (400x lens)

Immunofluorescence of paraffin embedded mouse brain using MCM2 (GB111162) at dilution of 1: 2000 (400x lens)

Immunofluorescence of paraffin embedded rat thymus using MCM2 (GB111162) at dilution of 1: 2000 (400x lens)




Storage

Storage Store at -20°C for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


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