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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MCP5 rabbit polyclonal antibody |
Gene Name: | C-C motif chemokine 12 |
Synonyms: | MCP-1-related chemokine, Monocyte chemoattractant protein 5, Monocyte chemotactic protein 5, MCP-5, Small-inducible cytokine A12, Mcp5, Scya12, Ccl12 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MCP5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | Q62401 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 400-1: 1200 | kidney, lymph node, small intestine, small intestine+LPS |
Background
Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
Images
| Immunofluorescence of paraffin embedded mouse lymph node using mcp5 (GB112194) at dilution of 1:400 (400x lens) |
| Immunofluorescence of paraffin embedded mouse small intestine using mcp5 (GB112194) at dilution of 1:400 (400x lens) |
| Immunofluorescence of paraffin embedded mouse lymph node using mcp5 (GB112194) at dilution of 1:600 (500x lens) |
| Immunofluorescence of paraffin embedded mouse small intestine+LPS using mcp5 (GB112194) at dilution of 1:1200 (500x lens) |
| Immunofluorescence of paraffin embedded rat kidney using mcp5 (GB112194) at dilution of 1:400 (400x lens) |
| Immunofluorescence of paraffin embedded rat lymph node using mcp5 (GB112194) at dilution of 1:400 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
