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| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MDM1 rabbit polyclonal antibody |
Gene Name: | Nuclear protein MDM1 |
Synonyms: | MDM1, Mdm1 nuclear protein homolog (mouse), Mdm1 nuclear protein homolog, Nuclear protein double minute 1, Mdm4 transformed 3T3 cell double minute 1 p53 binding protein |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MDM1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Uniprot ID: | Q8TC05 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 300-1: 1000 | thyroid gland |
Background
This gene encodes a microtubule-binding nuclear protein that localizes to the centrioles of dividing cells and differentiating multiciliated cells and negatively regulates centriole duplication. The encoded protein is closely associated with the centriole barrel, and resides in the centriole lumen. Naturally-occurring mutations in the orthologous mouse gene are associated with age-related retinal degeneration.
Images
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Immunofluorescence of paraffin embedded human thyroid gland using MDM1 (GB111388) at dilution of 1:500 (200x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
