Reactivity: | M,R & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | MEF2A rabbit polyclonal antibody |
Gene Name: | Myocyte-specific enhancer factor 2A |
Synonyms: | Myocyte enhancer-binding factor 2, ADCAD1, MADS box transcription enhancer factor 2, Myocyte enhancer factor 2A, MEF2, Myocyte enhancer factor 2A, RSRFC4, RSRFC9, Mef2a, Serum response factor like protein 1 |
Immunogen: | Recombinant protein corresponding to Mouse MEF2A |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. | 53 kDa |
Observed MW. | 54 kDa |
Uniprot ID: | Q60929, Q2MJT0 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | cerebral cortex, brain, lung, spleen |
IHC/IF | Mouse, Rat | 1: 200-1: 800 | brain, heart, lung, ovary |
Background
MEF2A is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this protein could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1).
Images
Western blot analysis of mef2a (GB11965) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded mouse brain using mef2α (GB11965) at dilution of 1: 400 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse heart using mef2α (GB11965) at dilution of 1: 400 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse lung using mef2α (GB11965) at dilution of 1: 400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using mef2α (GB11965) at dilution of 1: 400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat heart using mef2α (GB11965) at dilution of 1: 400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat lung using mef2α (GB11965) at dilution of 1: 400 (400x lens) | |
Immunohistochemistry of paraffin embedded rat ovary using mef2α (GB11965) at dilution of 1: 400 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |