Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | MEOX 2 rabbit polyclonal antibody |
Gene Name: | Homeobox protein MOX-2 |
Synonyms: | Mesenchyme homeobox 2, Meox2, Gax, Mox-2, Mox2, Growth arrest-specific homeobox |
Immunogen: | Recombinantproteincorresponding to Mouse MEOX 2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | P32443, P39020 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 300-1: 1200 | placenta |
Background
Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
Images
Immunohistochemistry of paraffin embedded mouse placenta using MOX2 (GB111684) at dilution of 1:600 (400x lens) | |
Immunohistochemistry of paraffin embedded rat placenta using MOX2 (GB111684) at dilution of 1:600 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |