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Anti-MESDC2 Rabbit pAb (100 μl)
| Reactivity: | R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | LRP chaperone MESD |
Synonyms: | BOCA, KIAA0081, LDLR chaperone MESD, MESD, MESDC2, Mesoderm development protein |
Immunogen: | Recombinant protein corresponding to Mouse MESDC2 |
Uniprot ID: | Q9ERE7 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 25 kDa / 23 kDa |
Product Usage Information
WB | Rat | 1: 500-1: 1000 | placenta |
Background
Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs) . Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction . Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4 . May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells.
Images
| Western blot analysis of MESD (GB114504) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
