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| Reactivity: | H,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MKKS rabbit polyclonal |
Gene Name: | McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin |
Synonyms: | Protein Bbs6 homolog, Mkks, Bbs6, HMCS, KMS, McKusick Kaufman syndrome, MKS |
Immunogen: | Recombinant protein corresponding to Mouse MKKS |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 62 kDa |
Observed MW. | 62 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Rat | 1: 1000-1: 2000 | Kidney, colon, pancreas |
Background
MKKS also known as BBS6 is a probable chaperone given to the amino acid similarity to the chaperonin family of proteins and may play a role in protein processing in limb, cardiac and reproductive system development. The mutations in BBS6 have been linked to Bardet-Biedl syndrome (BBS) which is a genetically heterogeneous, autosomal recessive disorder characterized by usually severe pigmentary retinopathy, early onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation. It may also get involved in cellular organization processes, in particular relating to ciliary/flagellar and centrosomal activities.
Images
 | Western blot analysis of MKKS (GB113058) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
